How Your Body Clears Hormones, Stress Metabolites, and Everyday Toxins After 45

If you’ve noticed that caffeine, alcohol, supplements, stress, or even fragrances affect you differently than they used to, this episode will help explain why.

In this episode, Lauri explores how detox and methylation pathways work behind the scenes — and why these systems can feel more noticeable after 45 as hormones and genetics interact differently than before.

You’ll learn how:

• Detox and methylation function as daily biological systems, not cleanses
•  Estrogen changes increase the importance of detox pathways in midlife
•  Stress chemistry places added demand on clearance pathways
•  Key genes like COMT, GSTM1, MTHFD1, and NAT2 shape tolerance and recovery
•  Simple, consistent habits support detox without extremes

This episode is especially helpful if you’ve experienced increased sensitivity to caffeine or alcohol, stress that lingers longer, stronger reactions to supplements, or changes in sleep quality after 45.

Resources Mentioned:

View the Midlife Genomics Series — a six-part article series explaining what genomics is and how to understand your own results.

Visit my website at inspiredlivingforwomen.com to learn more about me and my work.

Get your free guide, The Oxygen Connection, to see how oxygen use, genetics, and glucose metabolism work together to shape steady energy after 45.